What is your role and what does your work focus on?
I am a Research Fellow in the Molecular Virology Group located at the HMRB (Level 7), focused on understanding the mechanism of action of a novel dengue virus inhibitor developed by Johnson & Johnson in collaboration with researchers at the University of Leiden. Currently, there are no antiviral drugs for dengue, and only one vaccine (QDenga) is licensed in some countries for children aged 6 to 16. My goal is to identify proteins that interact with this inhibitor in dengue-infected host cells using proximity-biotinylation to map the surrounding protein microenvironment. This work relies on collaboration with an exceptional proteomics and bioinformatics team. More broadly, I aim to leverage modern tools and big data to explore pathogen-host interactions and advance anti-pathogenic drug development.
Where did you work before joining CMPH?
Before joining CMPH, I worked as a senior research officer at the Walter and Eliza Hall Institute of Medical Research (WEHI) in Melbourne, focusing on malaria parasite-host interactions and malaria protein export (yes, malaria is a parasite, not a virus! 😉). Prior to that, I completed my PhD on malaria drug discovery at Griffith University Institute for Biomedicine and Glycomics in Brisbane, and I completed my Master’s and Bachelor’s degrees in Germany.
What journey brought you to this point in your career?
My journey began in Brisbane, where my PhD supervisor offered me a position after a three-month overseas internship during my Master’s. At the time, I hadn’t considered a three-year program overseas, but my supervisor saw potential in me that I didn’t recognise. I am forever grateful for her encouragement. After my PhD, I couldn’t imagine returning home; I wanted to explore more of the Australian science community and dive deeper into infectious disease research.
What is something you love most about your work?
I love the versatility of academic research—new techniques and tools are constantly emerging, which can be challenging to keep up with, but it’s also inspiring and motivating. I get paid to learn, discover, and grow— This must be the best job in the world 😊 I enjoy the multidisciplinary nature of my work; biological science now involves bioinformatics and data management. Additionally, we need to persuade funding bodies to support our research through well-crafted applications and collaborate with experts in the field that align with our research questions. And while I completely understand the power of communication and love engaging with peers, mentors, and support teams, I also enjoy days where I can focus on my experiments or analyses independently.
How do you like to relax or spend your spare time?
I love climbing, everything from bouldering, rope climbing, outdoor climbing. UrbanClimb just opened a new gym on Hindley Street and I am super excited about it! Otherwise, I love being outside and exploring nature through running, gardening and camping. I just moved to SA, I am excited to explore this beautiful state!